Chronic total occlusion (CTO) happens when a coronary artery is completely blocked with plaque for more than three months. CTO obstructs the flow of blood to the heart and can have severe effects on the health. When one or more of coronary arteries are completely blocked, the patients are at higher risk for a heart attack. A percutaneous coronary interventional (PCI) procedure is the appropriate treatment option for patients that have poor blood flow through one or more coronary arteries. The growth of the global chronic total occlusion market is attributed to the increasing demand of minimally invasive surgeries, rising prevalence of artery diseases, technological advancements and rising geriatric population. However, side effects and risks associated with CTO procedures and high cost of chronic total occlusion procedures are the major factor hindering the market growth.