Renal replacement therapy includes alternating hemodialysis, peritoneal dialysis, continuous renal replacement therapies (CRRTs), and hybrid therapies such as prolonged alternating renal replacement therapies (PIRRTs), which are prolonged alternating dialysis. Continuous renal replacement therapy (CRRT) is a dialysis technique used to treat critically sick, hospitalized patients admitted in the intensive care unit, which generally develops Acute Kidney Injury (AKI).