Meta-Analysis of population studies on the prevalence of chronic pain in UK – Pubrica
                     A Meta-Analysis of 
Population  Studies on the 
Prevalence of  Chronic 
Pain in UK
An Academic presentation by
Dr. Nancy Agnes, Head, Technical 
Operations, Pubrica  Group:
www.pubrica.com
Email: [email protected]
T O D AY ' S  D I S C U S S I O N
O u t l i n e
Factors associated with chronic pain 
 Limitations
Conclusions
Chronic pain, which includes illnesses like low back  
pain and osteoarthritis, was recently highlighted as  
one of the most common causes of disability  
worldwide by the Global Burden of Disease studies in 
 a meta-analysis study.
National governments have begun to acknowledge 
 chronic pain as a key concern and challenge for their 
 public health and healthcare systems, resulting in  
national plans and the convening of Pain Summits in  
countries such as the UK, US and Europe.
Contd...
As with other long-term conditions like cancer and cardiovascular disease,  
such initiatives emphasize the importance of accurate population-based  
estimates of chronic pain in helping to drive and inform policies of  
prevention and care, needs assessments, and surveillance of the impact of  
interventions.
Despite multiple high-profile national publications emphasizing the  
importance of chronic pain in the UK, there is little agreement on the  
country's pain burden.
According to one estimate, up to 8 million people in the UK suffer from  
chronic pain, which corresponds to a telephone poll of European citizens in  
which 13% of the UK population reported pain of moderate-to-severe 
 intensity that lasted for more than 6 months.
Estimates based on definitions more closely aligned with 
 those of the International Association for the Study of  
Pain: "pain that persists beyond normal tissue healing time,  
which is believed to be 3 months" was significantly higher  
than those cited in the European telephone survey.
The goal of this clinical meta-analysis study was to compile  
available data on the prevalence of various chronic pain  
classifications in the general population to generate much-  
needed, reliable, and current national estimates.
FACTORS ASSOCIATED WITH 
 CHRONIC PAIN
Numerous physical, psychological, and social variables  
contribute to chronic pain.
Risk factors have traditionally been categorized as  
"modifiable" or "non-modifiable," however, this bio-  
medico-centric approach to epidemiology does not  
always account for the intricate interplay between  
modifiable and non-modifiable parts of each risk factor.
The individual's explanation of these events and their  
impact on their life and health, on the other hand, is  
constantly changing, and this will affect their future  
health and life.

In addition, interventions that strengthen the
biopsychosocial  determinants of health can help to
porepvuelantion exporsure to riskre fdauctcoers fluintukered to chronic pain.
Age, gender, ethnicity and cultural background, socioeconomic  
status, and lifestyle and behaviour are all considered factors.
Identifying and managing modifiable risk factors and elements of  
risk factors may help avoid chronic pain or reduce its duration and  
severity.
Meta analysis research factors that cannot be treated with medicine  
are relevant to discuss in a clinical setting.
Contd...
Many of these are pertinent to chronic pain  
predictions, evaluations, treatment, and prognoses,  
while others will be crucial in searching for new  
therapeutic targets.
Chronic pain management requires
multidisciplinary, epidemiologically a  informed,
patient-centered approach. and
The prevalence of chronic pain in the UK is estimated  
to be 43% based on the highest quality research of  
general population samples.
Meta-analysis in research of chronic pain prevalence increases steadily with age, affecting up to 62%  
of the population over the age of 75, implying that the burden of chronic pain may rise even more as 
 the population ages if the incidence remains unchanged.
According to weighted averages, widespread chronic pain affects 14.2% of the population.
Between 10.4% and 14.3% of the population suffers from either moderately or severely restricting  
chronic pain, resulting in an estimated 7.9 million persons in the UK with this condition.
LIMITATIONS
Given the meta-analysis heterogeneity in this  
field, which stems from differences in how chronic  
pain is characterized in each study and the  
populations analyzed, chronic pain epidemiology  
was chosen.
The latter may impact the study's generalizability 
 to other people, regions, or countries.
Differences in study design also limit individual  
research findings.
Becauseofthesedistinctions,rigorousdatasynthesis,includingmeta-analysis,is  complicated 
in this subject.
Cross-sectionalstudies,inparticular,makeitchallengingtodemonstratecausation  and, as a
 result, to separate risk factors from chronic pain outcomes.
CONCLUSION
Pubrica offers the best Clinical Meta-analysis  
services for clinical industries for younger  
researchers.
We examine the best available statistics to  
show that chronic pain affects one-third to  
half of the population in the UK.
Contd...
Although prevalence data alone does not establish the need 
 
for care or prevention goals, reliable data on prevalence will 
 aid public health, and healthcare officials prioritize this  
fundamental cause of distress and disability in the general  
population.
Chronic pain's enormous global illness burden must be  
addressed by addressing the causes and effects of chronic  
pain at both the individual and population levels.
Modifiable risk factors (e.g. acute pain, lifestyle, and  
behaviour) must be addressed to avoid and lessen the  
burden of chronic pain, with the patient at the center of the  
care.
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