Ziqitza Limited Rajasthan - How effective are vaccines against Covid Mutant Variant
                     Ziqitza Limited Rajasthan - How effective are 
vaccines against Covid Mutant Variant?
With so many news headlines focusing on the variants 
and their potential to prolong the pandemic, it’s no 
wonder that people have become increasingly 
concerned that the vaccines won’t work as well against 
mutations.
But infectious disease doctors say that even if antibody 
levels drop in the months following vaccination, the 
immune system is complex and robust. We’ll be well 
protected against variants, they say, with a lower risk for 
disease, hospitalization, and death.
The key question is, just how well do the vaccines work 
against the variants?
According to experts, well enough that vaccinated 
people don’t need to worry too much about the current 
known variants. Ziqitza has gone through the data from 
vaccine clinical trials and real world evidence show that 
even in the face of variants, the coronavirus vaccines can 
prevent infection and drastically cut people’s chances of 
severe disease and hospitalization.
As everyone knows, there are two vaccines currently in 
use in our country. Dr Datar, Medical Director, 
Ziqitza Healthcare Ltd says they can prevent severe 
disease and death and definitely reduce infections. He 
further says after vaccination, if we get infection, it is 
known as breakthrough infection.
Only 0.02% to 0.04% – or two to four per 10,000 – of vaccinated 
persons saw breakthrough infections after Covid-19 vaccination, 
which is a very small number, but even these few infections could 
be explained partly by the higher exposure of the infected persons 
compared to the general population, and to the ongoing second 
surge in India.
In the midst of these variant discoveries, there are conflicting 
reports on vaccine efficacy. So, here’s a summary based on 
science of what we currently know, what we don’t know, and 
what we can infer. Let’s start by asking what exactly is immune 
escape? Should we worry about it? And what does it mean for 
those who are already vaccinated?
Variants of concerns are mutated forms of SARS-CoV-2 that are 
more infectious, can cause more severe disease, can evade 
some immune responses, or do any combination of the above. 
Immune escape variants have mutations that prevent them 
from being tagged by antibodies, generated either because of 
prior infection or due to vaccination.
Effective neutralizing antibodies can stick to specific parts of 
the spike protein on the virus, preventing it from attaching to 
the receptor on the cell. Therefore, antibodies have a major 
role to play in preventing infection, both after natural infection 
and vaccination.
Ziqitza Limited says while there is much to learn about 
emerging variants and how vaccines work against them, there 
is already much that we know. Headlines on “immune escape" 
variants may indeed be alarming, but they are also simplistic. 
The immune system is analogous to a complex machine with 
many parts and settings. It isn’t a switch that goes between 
“on" and “off".
Many of these laboratory tests check how well antibodies 
recognize and prevent variants from attaching to cells. Serum 
is the fluid component of blood that contains antibodies. It is 
taken from those who have been vaccinated and is tested 
against variants.
Some of these tests have demonstrated reduced 
neutralization in immune escape variants. 
 
As per the observation done by Ziqitza Limited Rajasthan so 
far, there have been no reports of widespread mortality in 
those who have been exposed to any lineage of SARS-CoV-2 
after receiving both doses of any vaccine. This may change 
over time, but after hundreds of millions of vaccinations, this 
should be a cause of optimism. Vaccines are indeed saving 
lives.
In the future, updated booster shots tailored to specific variants 
could strengthen the immune response to variants. Researchers 
are looking into different approaches to combat variants right 
now, but the vaccines we have are powerful tools in reducing the 
healthcare burden of the pandemic. To sum up, all vaccines may 
not work equally well against all variants in preventing covid-19, 
but if they can keep people alive, they have met a primary 
objective.
Ziqitza Healthcare Ltd is Asia’s largest emergency medical service 
provider company and one of the fastest-growing holistic 
healthcare solution platforms in India. Be it Rural or Urban space 
ZHL Rajasthan & Ziqitza Limited Rajasthan has also contributed 
in saving more than 30 Million lives. Ziqitza Healthcare is also a 
pioneer in the ambulance services business in India, the vast 
experience and knowledge make it more viable to extend its 
services into this segment. Being a “one-stop solution" for 
corporate wellness & holistic healthcare for giant corporations, 
Ziqitza Limited also offers turnkey solutions that include 
Ambulance at the Site, Wellness at Workplace, Telehealth 
Services for Employees, Medical Rooms, Doctors on Site, and 
Occupational Health Therapies, among others.