3D Bioprinting Technology.
                     3D Bioprinting Technology
What Is 3D Bioprinting?
• 3D Bioprinting is a form of additive manufacturing that uses cells and other 
biocompatible materials as “inks”, also known as bioinks, to print living structures 
layer-by-layer which mimic the behavior of natural living systems.
Source: www.allevi3d.com
How does 3D bioprinting work?
• 3D bioprinting starts with a model of a structure, which is recreated layer-by-layer out 
of a bioink either mixed with living cells, or seeded with cells after the print is 
complete. 
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Analyze the geometry of the model
• 3D model file is then fed into a slicer a specialized kind of computer program which 
analyzes the geometry of the model and generates a series of thin layers, or slices, 
which form the shape of the original model when stacked vertically. 
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Final stage
• Once a model is sliced, the slices are transformed into path data, stored as a g-code 
file, which can be sent to a 3D bioprinter for printing.
• Once all of the g-code commands are completed, the print is done and can be 
cultured or seeded with cells as part of a biostudy.
Source: www.allevi3d.com
Why is bioprinting important?
• The scientific community has already succeeded in bringing together multidisciplinary 
teams of researchers, physicians, and engineers to take on the biggest challenges to 
human health, and 3D bioprinting is an exciting new tool with the potential to 
eliminate the organ transplant waiting list.
Source: www.allevi3d.com
Bioprinting For Pharmaceutical Development
• For pharmaceutical development, 3D bioprinting offers a means of testing drugs 
faster, at a lower cost, and with better biological relevance to humans than animal 
testing.
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Bioprinting For Biomedical Devices 
• In the biomedical devices field, 3D bioprinting has enabled new developments such as 
sugar stents to help surgeons join veins with fewer complications, and systems for 
improved drug delivery, among others.
Source: www.allevi3d.com
Bioprinting For Organ Replacement
• As bioprinting evolves, it will become possible to use a patient’s own cells to 3D print 
skin and bone grafts, organ patches, and even full replacement organs.
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Bioprinting For target treatments 
• Personalized and regenerative medicine continue to grow in popularity, and 3D 
bioprinting will give doctors and researchers the tools to better target treatments and 
improve patient outcomes.
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Challenges of 3D bioprinting
• The most burning issue is the question of regulation as an up-to-date, comprehensive 
set of rules for bioprinting has not yet been drafted. 
• That might be very dangerous since the black market for printed organs might thrive 
the most if regulations are not sufficiently strict and precise.
Source: www.allevi3d.com