The main difference between colleges and universities is the type of programs and degrees they offer, as well as their size and focus: Programs Colleges typically offer undergraduate programs, while universities offer a wider range of programs, including undergraduate, graduate, and Ph.D. degrees. Size Colleges are usually smaller than universities, with smaller enrollment numbers. Focus Colleges often focus on practice-oriented training, while universities concentrate on scientific research. Curriculum University programs may have more rigid curriculum structures, leaving less flexibility for students to tailor their course selections.