Arsenic Trioxide A sterile injectable solution
                     Arsenic Trioxide: A sterile 
injectable solution
ARSENOX is an arsenical indicated for induction of remission and consolidation in patients 
with acute promyelocytic leukemia (APL) who are refractory to, or have relapsed from, retinoid 
and anthracycline chemotherapy, and whose APL is characterized by the presence of the 
t(15;17) translocation or PML/RAR-alpha gene expression.

Effects of Arsenic Trioxide
Get emergency medical help if you have signs of an allergic reaction: hives; difficult 
breathing; swelling of your face, lips, tongue, or throat. 
Arsenic trioxide can cause a condition called differentiation syndrome, which affects 
blood cells and can be fatal if not treated. This condition may occur within 1 days to 
2 months after you start taking arsenic trioxide.
Seek medical help right away if you have symptoms of differentiation syndrome: 
fever, cough, trouble breathing; dizziness; rash; decreased urination; rapid weight 
gain; or swelling in your arms or legs.
Precautions
• APL Differentiation Syndrome- Nine of 40 patients with APL treated with TRISENOX, at a 
dose of 0.15 mg/kg, experienced the APL differentiation syndrome. High-dose steroids 
have been administered at the first suspicion of the APL differentiation syndrome and 
appear to mitigate signs and symptoms.
• Carcinogenesis- The active ingredient of TRISENOX, arsenic trioxide, is a human 
carcinogen. Monitor patients for the development of second primary malignancies.
• Embryo-Fetal Toxicity- TRISENOX can cause fetal harm when administered to a pregnant 
woman. Arsenic trioxide was embryolethal and teratogenic in rats when administered on 
gestation day 9 at a dose approximately 10 times the recommended human daily dose on 
a mg/m² basis.
• Laboratory Tests- The patient’s electrolyte and glucose levels, as well as hepatic, renal, 
hematologic and coagulation profiles should be monitored at least twice weekly, and more 
frequently for clinically unstable patients during the induction phase and at least weekly 
during the consolidation phase.
Availability
Buy Arsenic Trioxide online from various generic medicine suppliers at a 
reasonable price. The Indian Pharma is one of the best generic medicine 
suppliers, supplying medicines for more than 7 years.