Uploaded on Jul 24, 2019
Maball 100 mg (Rituximab) Injection
Maball 100 mg (Rituximab) Injection
Maball 100 mg (Rituximab) Injection | uses,dosage,side effects,price india MILLION HEALTH PHARMACEUTICALS DESCRIPTION Maball is a anticancer medicine which prevents the growth and spread of cancer cells in the body. Maball also indicated for the treatment of Non- Hodgkins lymphoma or chronic lymphocytic and with combination with another anticancer drugs like methotrexate is used for rheumatoid arthritis symptoms in adult treatment. Maball with steroid regimen combination is given for the treatment of some rare disorders which cause blood vessels and other tissues inflammation in the body. INDICATION Maball 100mg and hyaluronidase human injection are given alone or combination with another drugs to treat certain types of non- Hodgkin's lymphoma and chronic lymphocytic leukemia (cancer start in WBC). Maball 100mg injection is also used with methotrexate (Otrexup, Rasuvo, Xatmep, others) for the treatment rheumatoid arthritis symptoms in adults that have been already treated with a some type of regimen known as tumor necrosis factor (TNF) inhibitor. PHARMACODYNAMIC new type of "targeted" cancer treatment and an integral part of the body's immune system. Naturally the body build antibodies in along with to an antigen which has entered the body and attach to the antigen for destruction by the immune system. An essential cells only aimed by monoclonal antibiotics, they may leads to less toxicity to healthy cell and it is usually treatment recommended only for cancers in which antigens (and the respective antibodies) have been already identified. Maball works by linking to the CD20 antigen on normal and malignant B- cells. Hence the body's essential immune security are initiated to attack and kill the marked B-cells. Stem cells i.eyoung cells in the bone marrow which will grow into the various cell types and do not have the CD20 antigen. After treatment,CD20 antigen allows healthy B-cells to multiply PRODUCT DETAILS Brand : Maball Ingredients : Rituximab Strength : 100mg Manufactured : Hetero Package : injection PHARMACOKINETICS ABSORPTION Not available DISTRIBUTION volume of distribution is 3.1 L METABOLISM Maball 100mg metabolized by human antimurine antibody production. EXCRETION not available The half life of NHL is 22 days and for RA is 18.0 days, GPA and microscopic polyangitis is 23 days. DOSAGE MANAGEMENT Maball is recommended to administer only through intravenous infusion not by IV push or bolus. ADMINISTRATION Take an Maball amount and diluted to final concentration of 1 mg/ml upto 4 mg/ml as infusion (containing either 0.9% Nacl or 5% dextrose in water). Invert gently the bag and mix the solution. Dispose unused drug left in vial. OVERDOSAGE: If the patients had high dose of Maball then seek immediately to the emergency department or poison control help line. Please consult the doctor for further clarification. PRECAUTIONS Allgeric condition against Maball 100mg or any other medication informs your doctor. Concerning your past history of drug used which include in prescription, non-prescription, vitamins &supplements, nutritional products just inform the doctor. While using Maball 100mg do not take any vaccination or immunization without taking advice from doctors. Avoid use of Maball 100mg if you are pregnant. It will harm the baby unborn, while using Maball 100mg use correct birth control to prevent pregnancy and for at least 2 weeks after your treatment ends. SIDE EFFECTS Common effects: fever and chills (flu like symptoms) Less common side effects: Weakness; nausea; headache; cough; dyspnea; pharyngitis DRUG INTERACTION Maball 100mg drug interaction has limited data is available at present. Combination with fludarabine or cyclophosphamide has no effects in pharmacokinetics in CLL patients. Combination with methotrexate had no effects in pharmacokinetics. CONTRAINDICATIONS Hypersensitivity or murine proteins. Active severe infectons in rheumatoid arthritis Uncontrolled cardiac disease. PREGNANCY CategoryC : animal studies reproduction shown an adverse effect on the fetus. The drug has no sufficient and well controlled studies in humans, using in pregnant women benefits by warrant use of the drug. LACTATION Maball 100mg excreted into human milk is unknown. Due to the drug belongs to large protein molecule, no information is available. Women should not breast feed during Maball 100mg treatment and 12 months following last dose. STORAGE Store at 2°C – 3°C Use the drug before expiry date Protected from direct sunlight Do not freeze or shake. Keep away from the childerns Discard the unused drug by asking the advice from doctor or pharmacist. MISSED DOSE If a dose missed to take at the time then have it suddenly before next dose timing, if time reach for next dose, then skip missed dose and continue and continue the regular schedule. Do not have 2 dose at a same time. Contact Us: PHONE NO +91-9940472902 EMAIL [email protected] WEBSITE URL https ://millionpharma.com/maball-100mg.php
Comments