Olimab 60mg injection


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Uploaded on Jul 30, 2019

Olimab 60mg injection

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Olimab 60mg injection

Olimab 60mg injection (Denosumab) - MHP MILLION HEALTH PHARMACEUTICALS olimab 60mg , olimab 60mg injection , olimab 60mg price in India DESCRIPTION Olimab 60mg is a human monoclonal antibody for the treatment of osteoporosis, treatment-persuaded bone loss, metastases to bone, and giant cell tumor of bone.  Olimab 60mg injection is contraindicated in people with low blood calcium levels. Olimab 60mg is prescription drug which is used under the guidance of medical oncologist. INDICATION • Olimab 60mg injection Indicated for treatment ofosteoporosis at high risk postmenopausal women with (end of menopause/ change of life), whose have serious problem of fractures raised or who failed to other medication of osteoporosis. • Olimab 60mg Indicated for treatment of Breast cancer in women whose taking certain treatment which make severe their risk of fractures and bone loss in men with prostate cancer. • Indicated for treatment in adults and some adolescents with giant cell tumor of bone which cannot treat with surgery / surgery is not possible is treated with Olimab 60mg injection. MECHANISM OF ACTION Denosumab (Olimab 60mg )mechanism by aiming a protein called RANKL, which is required for new osteoclasts to be made and to function. This promote to inhibit further breakdown of bone and reduces the risk of problems caused by secondary bone cancer, such as fractures. It can also promote to decreased pain caused by secondary bone cancer. PRODUCT DETAILS Brand :Olimab Ingredients : Denosumab Strength : 60mg Manufactured : Intas Pharmaceuticals Package : 1 injection in a prefilled syringe Price : olimab 60mg price in India olimab 60mg ADME • Peak plasma concentration: 6.75mcg/mL • Tmax: 10days • Without aggregation in Olimab 60mg  pharmacokinetics with duration was noticed upon multiple dosing of 60 mg SC administered once every 6 months. • Pharmacokinetics of Olimab 60mg injection will not affected by the binding antibodies formation. • Half-life is 25.4 days. DOSAGE MANAGEMENT For adult : The prescribed dose for Osteoporosis is olimab 60mg SC (subcutaneously) once every 6 months The prescribed dose for Androgen Deprivation induced bone loss is olimab 60mg injection SC q6months. The prescribed dose is Glucocorticoid induced osteoporosis olimab 60mg SC q6months. The prescribed dose is Aromatase inhibitor induced bone loss olimab 60mg injection SC q6months For pediatric : The prescribed dose is 13 years and older and 45kg or more for Giant Cell Tumor of bone: The recommended dose is of 120mg Olimab 60mg tablet given SC, with additional 120mg doses on days 8 and 15 of the 1st month treatmentevery 4 weeks. OVERDOSE No experienced with Olimab 60mg injection overdose. If occurs take the patient to emergency department and call poison control PRECAUTIONS • Before starting denosumab should be corrected. Hypocalcemia may worsen, specifically in patients with renal impairment. Sufficiently supplement patients with calcium and vitamin D. • Olimab 60mg injection has negative effects of immuno-suppressantsmay improve. Especially the harm for severe infections may be raised. Discuss with your doctor of any immuno- suppressive drugs you early consume. • While treatment with Olimab have Osteonecrosis of the jaw (ONJ) has been reported with denosumab – check for symptoms. SIDE EFFECTS Common side effects for the patient taking Olimab 60mg injection : • Nausea • Fatigue • Muscle weakness • Hypophosphatemia. SIDE EFFECTS Less common side effects for patients taking Olimab 60mg : • Diarrhae • Shortness of breath • Hypocalcemia • Joint pain • Hypocalcemia • Cough • Arthralgia • Limb pain • Eczema • Headache • Eczema • Rash DRUG INTERACTION No formal drug-drug interaction with denosumab (Olimab 60mg) during trials. When concomitant use with some anticancer drug, orthopedic drugs, vaccines will lead to risk of adverse effects can be increased CONTRAINDICATION: Olimab 60mg injection is contraindicated in Hypocalcemia Pregnancy Hypersensitivity PREGNANCY category C The Olimab 60mg which has no enough data in pregnant women to convey any drug analog risk for adverse development outcomes the drug in pregnant women is contraindicated for use because it may cause serious risk to the fetus. LACTATION: Olimab 60mg injection is excreted into human milk is not known. Since possible for severe side effects occurs in nursing infants from Olimab 60mg injection. Avoid breastfeeding during treatment of Denosumab. STORAGE Store at 2°C to 8°C in the original container. Avoid freeze. Before to administration keep at room temperature. Olimab 60mg protect from direct light and heat. MISSED DOSE: If Olimab 60mg dose is missed then have the dose immediately before next dose duration. Next dose time reaches then left off the missed dose and follows regular schedule. Avoid taking double dose at same time. Please consult the doctor for further information. CONTACT US PHONE NO : +91-9940472902 EMAIL ID [email protected] WEBSITE URL  https://millionpharma.com/olimab-60mg.php KEYWORDS olimab 60mg , olimab 60m injection , olimab 60mg price in india