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Know Everything 
About Estradiol
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What Is Estradiol ?
This medication is a female hormone. It is used by women to help 
reduce symptoms of menopause (such as hot flashes, vaginal 
dryness). These symptoms are caused by the body making less 
estrogen. If you are using this medication to treat symptoms only 
in and around the vagina, products applied directly inside the 
vagina should be considered before medications that are taken by 
mouth, absorbed through the skin, or injected. Certain estrogen 
products may also be used by women after menopause to prevent 
bone loss (osteoporosis). However, there are other medications 
(such as raloxifene, bisphosphonates including alendronate) that 
are also effective in preventing bone loss and may be safer. These 
medications should be considered for use before estrogen 
treatment. Certain estrogen products may also be used by men 
and women to treat cancers (certain types of prostate cancer, 
breast cancer that has spread to other parts of the body) and by 
women who are not able to produce enough estrogen. Buy E
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How it is used ?
Read the Patient Information Leaflet if available from your pharmacist 
before you start using this medication and each time you get a refill. If 
you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by 
your doctor. You may take it with food or right after a meal to prevent 
stomach upset.
If you are taking the extended-release tablets, do not crush, chew, or 
dissolve them. Doing so can release all of the drug at once, increasing 
the risk of side effects. Also, do not split extended-release tablets 
unless they have a score line and your doctor or pharmacist tells you 
to do so. Swallow the whole or split tablet without crushing or 
chewing.
The dosage is based on your medical condition and response to 
treatment.
Take this medication regularly to get the most benefit from it. To help 
you remember, take it at the same time(s) each day as directed. You 
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Tell your doctor if your condition does not improve or if it worsens.
Possible Side Effects of Estradiol 
Stomach upset, nausea/vomiting, bloating, breast tenderness, 
headache, or weight changes may occur. If any of these effects 
persist or worsen, tell your doctor or pharmacist promptly.
Tell your doctor promptly if you see the tablet in your stool.
Tell your doctor right away if you have any serious side effects, 
including: mental/mood changes (such as depression, memory 
loss), breast lumps, unusual vaginal bleeding (such as spotting, 
breakthrough bleeding, prolonged/recurrent bleeding), increased 
or new vaginal irritation/itching/odor/discharge, severe 
stomach/abdominal pain, persistent nausea/vomiting, yellowing 
eyes/skin, dark urine, swelling hands/ankles/feet, increased 
A very serious allergic reaction to this product is rare. 
thirst/urination.
However, get medical help right away if you notice any 
symptoms of a serious allergic reaction, including: rash, 
itching/swelling (especially of the face/tongue/throat), severe 
dizziness, trouble breathing.
This is not a complete list of possible side effects. If you 
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pharmacist.
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can  order Estradiol online from anywhere, but you can only 
do that if the doctor sends you the same prescription.
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