Uploaded on Jan 10, 2023
PPT on Genealogical DNA test
Genealogical DNA test
GENEALOGICAL DNA TEST INTRODUCTION GENETIC ANCESTRY TESTING, OR GENETIC GENEALOGY, IS A WAY FOR PEOPLE INTERESTED IN FAMILY HISTORY (GENEALOGY) TO GO BEYOND WHAT THEY CAN LEARN FROM RELATIVES OR FROM HISTORICAL DOCUMENTATION. 2 SOURCE: MEDLINEPLUS.GOV EXAMINATION OF DNA VARIATIONS EXAMINATION OF DNA VARIATIONS CAN PROVIDE CLUES ABOUT WHERE A PERSON'S ANCESTORS MIGHT HAVE COME FROM AND ABOUT RELATIONSHIPS BETWEEN FAMILIES. 3 SOURCE: MEDLINEPLUS.GOV PATTERNS OF GENETIC VARIATION CERTAIN PATTERNS OF GENETIC VARIATION ARE OFTEN SHARED AMONG PEOPLE OF PARTICULAR BACKGROUNDS. THE MORE CLOSELY RELATED TWO INDIVIDUALS, FAMILIES, OR POPULATIONS ARE, THE MORE PATTERNS OF VARIATION THEY TYPICALLY SHARE. 4 SOURCE: MEDLINEPLUS.GOV Y CHROMOSOME TESTING VARIATIONS IN THE Y CHROMOSOME CAN BE USED TO EXPLORE ANCESTRY IN THE DIRECT MALE LINE. ONLY INDIVIDUALS WITH A Y CHROMOSOME (TYPICALLY MALES) CAN HAVE THIS TYPE OF TESTING DONE. 5 SOURCE: MEDLINEPLUS.GOV Y CHROMOSOME TESTING CONT. BECAUSE THE Y CHROMOSOME IS PASSED ON IN THE SAME PATTERN AS ARE FAMILY NAMES (SURNAMES) IN MANY CULTURES, Y CHROMOSOME TESTING IS OFTEN USED TO INVESTIGATE QUESTIONS SUCH AS WHETHER TWO FAMILIES WITH THE SAME SURNAME ARE RELATED. 6 SOURCE: MEDLINEPLUS.GOV MITOCHONDRIAL DNA TESTING THIS TYPE OF TESTING IDENTIFIES GENETIC VARIATIONS IN MITOCHONDRIAL DNA. ALTHOUGH MOST DNA IS PACKAGED IN CHROMOSOMES WITHIN THE CELL NUCLEUS, CELL STRUCTURES CALLED MITOCHONDRIA. 7 SOURCE: MEDLINEPLUS.GOV MITOCHONDRIAL DNA TESTING CONT. MITOCHONDRIAL DNA TESTING CAN BE USEFUL FOR GENEALOGY BECAUSE IT PRESERVES INFORMATION ABOUT FEMALE ANCESTORS THAT MAY BE LOST FROM THE HISTORICAL RECORD BECAUSE OF THE WAY SURNAMES ARE OFTEN PASSED DOWN. 8 SOURCE: MEDLINEPLUS.GOV SINGLE NUCLEOTIDE POLYMORPHISM TESTING THESE TESTS EVALUATE LARGE NUMBERS OF INDIVIDUAL VARIATIONS (SINGLE NUCLEOTIDE POLYMORPHISMS OR SNPS) ACROSS A PERSON’S ENTIRE GENOME. THE RESULTS ARE COMPARED TO SIMILAR SNPS IN A TESTING DATABASE TO PROVIDE AN ESTIMATE OF A PERSON'S ETHNIC BACKGROUND. 9 SOURCE: MEDLINEPLUS.GOV EXAMPLE FOR EXAMPLE, THE PATTERN OF SNPS MIGHT INDICATE THAT A PERSON'S ANCESTRY IS APPROXIMATELY 50 PERCENT AFRICAN, 25 PERCENT EUROPEAN, 20 PERCENT ASIAN, AND 5 PERCENT UNKNOWN. 1 0 SOURCE: MEDLINEPLUS.GOV THANK YOU
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