Surviving Sepsis guidelines 2022
                     SURVIVING 
SEPSIS 
GUIDELINES 2022
INTRODUCTION
Updated global adult sepsis guidelines, 
released in October 2022 by the Surviving 
Sepsis Campaign (SSC), place an increased 
emphasis on improving the care of sepsis 
patients after they are discharged from the 
intensive care unit (ICU) and represent 
greater geographic and gender diversity than 
previous versions.
Source: www.sccm.org
NEW GUIDELINES
The new guidelines specifically address the 
challenges of treating patients experiencing 
the long-term effects of sepsis. Patients often 
experience lengthy ICU stays and then face a 
long, complicated road to recovery. 
In addition to physical rehabilitation 
challenges, patients and their families are 
often uncertain how to coordinate care that 
promotes recovery and matches their goals 
of care.
Source: www.sccm.org
PERFORMANCE 
IMPROVEMENT 
PROGRAM
For hospitals and health systems, they 
recommend using a performance 
improvement program for sepsis, including 
sepsis screening for acutely ill, high-risk 
patients and standard operating procedures 
for treatment.
Source: www.sccm.org
MEASURING BLOOD 
LACTATE
For adults suspected of having sepsis, they 
suggest measuring blood lactate.
Source: www.sccm.org
TREATMENT AND 
RESUSCITATION
Sepsis and septic shock are medical 
emergencies, and they recommend 
treatment and resuscitation begin 
immediately.
Source: www.sccm.org
SEPSIS-INDUCED 
HYPOPERFUSION
For patients with sepsis-induced 
hypoperfusion or septic shock, we suggest 
that at least 30 mL/kg of IV crystalloid fluid 
be given within the first 3 hours of 
resuscitation.
Source: www.sccm.org
FLUID RESUSCITATION
For adults with sepsis or septic shock, they 
suggest using dynamic measures to guide 
fluid resuscitation over physical examination 
or static parameters alone.
Source: www.sccm.org
ALTERNATIVE DIAGNOSES
For adults with suspected sepsis or septic 
shock but unconfirmed infection, thee 
recommend continuously reevaluating and 
searching for alternative diagnoses and 
discontinuing empiric antimicrobials if an 
alternative cause of illness is demonstrated 
or strongly suspected.
Source: www.sccm.org
TIME-LIMITED COURSE 
OF RAPID INVESTIGATION
For adults with possible sepsis without shock, 
thee suggest a time-limited course of rapid 
investigation and if concern for infection 
persists, the administration of antimicrobials 
within 3 hours from the time when sepsis 
was first recognized.
Source: www.sccm.org
MECHANICAL VENOUS 
THROMBOEMBOLISM 
PROPHYLAXIS
For adults with sepsis or septic shock, they 
suggest against using mechanical venous 
thromboembolism prophylaxis in addition to 
pharmacologic prophylaxis, over 
pharmacologic prophylaxis alone.
Source: www.sccm.org